ABSTRACT
Prostaglandin analogues, latanoprost and travoprost, and one of the prostamides, bimatoprost, are widely used in glaucoma practice with their efficacious intraocular pressure-lowering effect. Treatment-related trichomegaly, increase in periocular pigmentation and adnexal hair growth are well-known periocular changes. But recently, a new and infrequent side effect called prostaglandin-associated periorbitopathy characterized by deepening of the upper lid sulcus, ptosis, enophthalmus, regression in dermatochalasis and lower lid lateral orbital fat pad prolapsus has been determined. In this case report, we wanted to present this rare side effect in three glaucoma patients who received bimatoprost and travoprost and to remind related fundamental physiopathology.
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