ABSTRACT

Chronic nonspesific inflammation and fibrosis is the most histopatholgy in lacrimal sac specimens obtained during DCR.Lacrimal sac neoplasm was detected in 1.61% of cases and was suspected clinically in 3.22% of cases. In conclusion rutine lacrimal sac biopsy is unnecessary, it should be performed in suspicious cases.

The most common histopathologic findings in lacrimal sacs were chronic nonspesific inflammation (n: 54, 87.09%), fibrosis (n: 17, 27.41%), dystrophic calcification (n: 14, 22.58%). Less common findings were granulation tissue (n: 9, 14.51%), hyaline connective tissue (n: 3, 4.83%), capiller vascular proliferation (n: 2, 3.22%), fibroblastic proliferation (n: 1, 1.61%), dissociated epithelial cells (n: 1, 1.61%), and in one patient lymphoma was detected (1.61%). In total 1 (1.61%) sac demostrated significant pathology. Clinical suspicion was persent in 2 patients before surgery.

Lacrimal sac specimens taken from the posterior sap of 59 patients' 62 sacs undergoing external DCR with U sap technique between April 2004 and May 2006 were examined. Preoperative clinical diagnosis was primary aquired nasolacrimal duct obstruction (PANDO) in 57 patients, seconder nasolacrimal duct obstruction (SNDO) in 2 patients. The clinical features of the patients with abnormal histopathological results were reviewed retrospectively to determine if the pathology was suspected before or at the time of the surgery.

To investigate the histopathologic findings of lacrimal sac specimens obtained during external dakriyosistorinostomi (DCR).