Original Article

Evaluation of the Effects of Menstrual Cycle on Anterior Chamber Parameters as Measured with Pentacam

10.4274/tjo.43.97759

  • Arzu Seyhan Karatepe
  • Melis Palamar Onay
  • Sait Eğrilmez
  • Ayşe Yağcı

Received Date: 26.07.2012 Accepted Date: 15.10.2012 Turk J Ophthalmol 2013;43(1):15-18

Pur­po­se:

To evaluate the effects of endogenous gonadotropic hormones (follicle-stimulating hormone, luteinizing hormone) and sex steroids (progesterone, estrogen) to anterior segment parameters.

Ma­te­ri­al and Met­hod:

Thirty healthy females who had a menstrual cycle of 28±1 day and with a mean age of 36.5±7.56 (range, 20 – 46) years were included in the study. Starting from the first day of their cycle, Pentacam Scheimpflug camera measurements were performed on the 1st, 3rd, 7th, 12th, 16th, 21st, 26th, and 28th days. The central corneal thickness, anterior chamber depth, anterior segment volume, keratometric values, anterior chamber angle value, and pupilla diameter of both eyes were evaluated. Repeated measures analysis of variance test was used for statistical analysis.

Re­sults:

No difference that reaches statistical significance was found in the means of central corneal thickness, anterior chamber volume, keratometric values, anterior chamber angle, and pupilla diameter between the days. Mean anterior chamber depth measurement of the right eyes on the 1st day was 2.72±0.44 mm, whereas it was 2.77±0.46 mm on the 26th day. Mean anterior chamber depth measurement of the left eyes on the 1st day was 2.74±0.42 mm, whereas it was 2.80±0.43 mm on the 26th day. This increment of anterior chamber depth value from the 1st to the 26th days was found to be statistically significant (p≤0.05).

Dis­cus­si­on:

Progesterone and estrogen that rise in the second half of the menstrual cycle might have a deepening effect on the anterior chamber. These findings should be further investigated with more profound studies that also evaluate the hormonal values and their correlations with anterior segment parameters.

Keywords: Anterior chamber, cornea, estrogen, menstrual cycle, Pentacam, progesterone

Full Text (Turkish)