Original Article

Trabeculectomy with mitomycine C (MMC) in cases with aphakic and pseudophakic open angle glaucoma - Original Article

  • M. Sinan Saricaoglu
  • Betül Fidan
  • Ahmet Karakurt
  • Hikmet Hasiripi

Received Date: 26.01.2007 Accepted Date: 22.01.2008 Turk J Ophthalmol 2008;38(1):22-27

Purpose: To investigate the efficacy and safety of trabeculectomy with mitomycine C (MMC) in ases with aphakic and pseudophakic open angle glaucoma. Methods: We retrospectively evaluated the results of trabeculectomy with MMC performed on 14 pseudophakic and 9 aphakic open angle glaucoma patients. Intraoperative MMC was applied in a concentration of 0.2 mg/ml for 3 minutes. Postoperative mean follow-up time was 29.4±16.8 months. Preoperative and postoperative data were compared statistically. Statistical significance was accepted as p Results: Mean age of the cases was 52.1±16 years. Sixteen cases were male and 7 cases were female. Anterior chamber lens was present in 4 and posterior chamber lens in 10 pseudophakic patients. Mean preoperative basal intraocular pressure (IOP) was 34.9±1.6 mmHg, whereas it was measured as 17.4±0.7 mmHg in the last control. The postoperative antiglaucomatous medication number decreased to 1.2±0.2 from the preoperative mean value of 2.7±0.2. The decrease at IOPs and in the number of antiglaucomatous medication were statistically significant (p Conclusion: Trabeculectomy with MMC is an effective and safe surgical technique in cases with aphakic and pseudophakic open angle glaucoma patients But it is technically difficult because of the previous surgical procedures and the presence of an intraocular lens. So the surgeon should be very careful about the intraoperative and postoperative complications and hold in mind that there could be a need for additional medical therapy or surgical interventions.

Keywords: Aphakia, pseudophakia, trabeculectomy, mitomycin C

Full Text (Turkish)