Original Article

The comparison of the Effects of the Pilocarpine Induced Accommodation with regard to Cyloplegia on Lens Thickness between Axial Myopia and Emmetropia

  • Orkun Müftüoğlu
  • Banu Melek Hoşal
  • Güler Zilelioğlu

Received Date: 22.11.2007 Accepted Date: 22.02.2008 Turk J Ophthalmol 2008;38(2):97-102

Purpose:

To compare the effects of the pilocarpine induced accommodation with regard to cyloplegia on lens thickness between axial myopia and emmetropia.

Methods:

Twenty-seven subjects with unilateral axial myopia and more than 3 diopters of difference in spherical equivalent between two eyes of each subject were included in the study. The mean age of the subjects was 27.3 ± 8.1 (range: 14 to 43) years. Both eyes of all sub-jects underwent axial length and lens thickness measurements with ultrasound biometry under cyclopentolate 1% and pilocarpine 2%, respectively. The eyes with axial myopia (study group) were compared with same subjects fellow (control group) eyes with lower axial length.

Results:

The mean lens thickness under cyclopentolate was 3.78 ± 0.08 mm and 3.76 ± 0.10 mm in the axial myopia group and the control group, respectively. The mean lens thickness under pilocarpine was 3.96 ± 0.08 mm and 4.00 ± 0.08 mm in the axial myopia group and the control group, respectively. There was no statistically significant difference between the lens thickness of the axial myopia group and control group, under cyclopentolate (p>0.05) and pilocarpine (p>0.05), respectively. The mean increase in lens thickness after pilocarpine instillation with regard to cyloplegia was 0.20 ± 0.10 mm in the axial myopia group and 0.21 ± 0.10 mm in the control group. There was no statistically significant difference in increase in lens thickness after pilocarpine instillation with regard to cycloplegia between axial myopia and control gro-ups (p>0.05).

Conclusions:

There is no statistically significant difference in the effects of the pilocarpine induced accommodation with regard to cyloplegia on lens thickness between axial myopia and emmetropia.

Keywords: Axial myopia, lens thickness, accommodation

Full Text (Turkish)