Original Article

Effect of Age Factor on Corneal Cross-linking Treatment of Keratoconus Patients


  • Lokman Aslan
  • Ahmet Metin Baskan
  • Erdem Yüksel
  • Murat Aslankurt
  • Murat Özdemir

Received Date: 23.03.2012 Accepted Date: 08.08.2012 Turk J Ophthalmol 2012;42(6):450-453


To evaluate the effect of age on corneal cross-linking treatment in keratoconus patients.

Material and Method:

We retrospectively evaluated forty-nine eyes of 45 patients with keratoconus that were applied corneal cross-linking treatment. The patients were divided into three groups; pediatric, adolescent and adult. The first group (25 years old) consisted of 17 eyes. Preoperative best-corrected visual acuity (BCVA log-MAR), central corneal thickness (CCT), and maximum corneal steepness (MCS) were compared with postoperative 13.8±3.83-month follow-up values.


After the treatment, a statistically significant improvement in visual acuity was found in group 1 (p<0.50).Visual acuity improvement was not statistically significant in group 2 and group 3 (p=0.434, p=0.21, respectively). Log-MAR-visual acuity differences were not statistically significant among the groups (p=0.182). No statistically significant change was found in postoperative CCT values in all groups (p=0.353, p=0.308, p=0.692, respectively). MCS values did not change statistically significantly at the postoperative evaluation (p=0.605, p=0.574, p=0.266, respectively). There was no statistically significant difference when comparing the three groups (p=0.856). Maximum corneal flattening was observed in group 3, but it was not statistically significant (p=0.282).


It was determined that the results of corneal cross-linking treatment in keratoconus did not demonstrate any statistically significant changes among the age groups with respect to visual acuity, CCT and MCS values. (Turk J Ophthalmol 2012; 42: 450-3)

Keywords: Keratoconus, corneal cross-linking, age

Full Text (Turkish)