Case Report

Clinical Feature and Prognosis in Our Cases With Vogt-Koyanagi-Harada Syndrome

  • Mehmet Çıtırık
  • Murat Serkan Songur
  • Nilüfer Berker
  • Ufuk Elgin
  • Seyhan Sonar Özkan
  • Orhan Zilelioğlu

Turk J Ophthalmol 2009;39(1):70-75


To investigate the sexuality, age, and accompanying eye examination findings of cases that was diagnosed as Vogt-Koyanagi-Harada (VKH).

Material and Methods:

From 2002 to the 2008, 5 cases with VKH in SB Ankara Ulucanlar Eye Education and Research Hospital Uvea Clinic were involved in this study retrospectively. A complete ophthalmological examination including visual acuity, applanation tonometry, slit lamb examination after dilatation of pupils was evaluated at the beginning and follow-up period.


All follow-up patients were women (%100). The average age of cases was 30.40±12.99 years (13-46 years). Mean follow up period was 5±0.7 years (4-6 years). Ten eyes of 5 cases were involved. Bilateral exudative retinal detachment in 6 eyes (60%), Dalen-Fuchs nodules in preipheric retina in 6 eyes (60 %) keratic precipitates in 4 eyes (40%), cell in anterior chamber in 2 eyes (20%), posterior synechiae in 2 eyes (20%), and macular edema in 2 eyes (20%) were determined at the onset of the disease. High intraocular pressure was observed in 2 eyes (20%). Medical therapy was performed to all eyes (93.3%). Sequel keratic precipitates in 4 eyes (40%) and cataract in 2 eyes (20%) were found as anterior segment complications after the therapy. Sunset glow appearance of fundus in 10 eyes (100%), atrophic depigmented lesions in posterior pole of retina in 4 eyes (40%), vitreous condensation in 2 eyes (20%), macular scar in 2 eyes (20%), and paleness of optic disc secondary to previous papillitis in 1 eye (10%) were found as posterior segment complications after the therapy. During the follow-up, visual acuity increased in 7 eyes (37.39%), did not change in 1 eye (10%), and decreased in 2 eyes (20%).


VKH syndrome should be considered diagnosis in patients with bilateral exudative retinal detachment. Long-term visual prognosis is generally well with early diagnosis and treatment.

Keywords: Glaucoma, keratic precipitates, uveitis, Vogt-Koyanagi-Harada