Original Article

A New Diagnostic Tool For The Detection of Choroidal Neovascularization Secondary to Age-Related Macular Degeneration: Preferential Hyperacuity Perimetry - Original Article

  • Umut Asli Dinç
  • Melda Nursal Yenerel
  • Ebru Görgün
  • Murat Öncel
  • Demir Basar

Received Date: 16.11.2007 Accepted Date: 08.02.2008 Turk J Ophthalmol 2008;38(2):139-143

Purpose: To evaluate the efficacy of a new diagnostic tool for the diagnosis of choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) known as preferential hyperacuity perimetry (PHP) to detect and localize the lesion. Materials and Methods: Patients diagnosed to have CNV related to AMD were enrolled in the study. All participants were evaluated by fundus fluorescein angiography (FFA) after a detailed ophthalmic examination. Central 14°x14° visual field were tested PHP (Foresee PHP, Notalvision). Hyperacuity deviation map and hyperacuity defect maps were recorded by PHP. Patients having high false positive or false negative ratios were excluded. The correlation between the localization of CNV detected by FFA and the possible retinal localization determined by PHP was investigated. Results: Twenty eyes of 15 patients with a mean age of 70.6±7.1 years and a mean visual acuity of 0.3±0.2 were recruited in the study. In 7 eyes classic, in 3 eyes predominantly classic, in 3 eyes minimally classic, in 5 eyes occult CNV were detected by FFA. Only in 2 eyes pigment epithelium detachment (PED) was found. The estimated retinal localization demonstrated in hyperacuity defect map by PHP was found to be correlated with CNV localization by FFA in 18 eyes. Conclusion: In the majority of cases estimated retinal localization detected by PHP was correlated to CNV localization by FFA. PHP seems to be mostly effective for identifying central macular dysfunction in CNV secondary to AMD.

Keywords: Age-related macular degeneration, choroidal neovascularization, preferential hyperacuity perimetry

Full Text (Turkish)